Claude Science 自主设计蛋白质结合物应对致命蝎毒
原标题:Claude Science tackles deadly scorpion stings by designing protein binders from scratch
AI 摘要
Anthropic 的 Claude 在 Claude Science 研究环境中基本自主地设计了针对蝎子神经毒素的蛋白质结合物。Claude 针对来自四种蝎子的五种毒素生成了 318,484 个设计,在初始提示后自主工作 24 小时,随后研究团队用额外指令引导。实验室测试的 211 个设计中有 17 个符合结合物标准,其中两个最强候选与墨西哥蝎毒素 Cn2 紧密结合,但尚未验证是否真能作为抗毒血清。外部专家称这是有希望的第一步,两个独立实验室确认了结果。
正文节选
Claude Science tackles deadly scorpion stings by designing protein binders from scratch Anthropic's Claude largely autonomously designed protein binders targeting scorpion neurotoxins, which kill more than 3,250 people every year. These small protein molecules are shaped to latch onto a specific target molecule. Claude generated 318,484 designs for such protein binders targeting five toxins from four scorpion species. After an initial prompt, Claude worked on its own for 24 hours. The research t