Google Research 将 AI 智能体引入湿实验室实现闭环分子发现
原标题:Grounding AI agents in biological reality: Building blocks for autonomous wet labs
AI 摘要
Google Research 将 AI 智能体引入湿实验室,提出 VERID 框架作为实验室工作单元的语义数字孪生,基于开源 PyLabRobot 构建,使智能体能够感知物理状态并安全执行液体处理操作。研究还利用 DNA 适配体作为闭环分子发现的沙盒,在 myoglobin 和 α-thrombin 两个靶点上经过三轮设计-测试-迭代,将确认的命中率分别提升至 33.5% 和 42.1%,并让智能体自主识别和修正实验假象。
正文节选
October 16, 2026 Pooja Rao, Research Scientist, Petar Sirkovic, Software Engineer, and Annalisa Pawlosky, Research Scientist, Google We are bringing AI agents to the wet-lab bench at Google Research to navigate complex biological landscapes. By grounding agents in physical lab robotics, we can run fast closed-loop molecular design cycles where agents learn how to learn, ultimately discovering single-digit nanomolar protein binders for cancer targets. Frontier AI systems have the potential to tra