Google 用 Antigravity 加速抗菌肽发现
原标题:Accelerating the search for antimicrobial peptides with Google Antigravity
AI 摘要
Google DeepMind 发布文章介绍利用 Google Antigravity 加速抗菌肽(AMP)的发现。文章指出抗菌素耐药性到 2050 年可能导致每年 1000 万人死亡,而基因组测序产生了数十亿条天然氨基酸序列,其中大量蛋白功能未知。Google 开发的 ProtNLM 深度学习模型可直接从原始蛋白序列预测生物功能,为 UniProt 中数百万条未命名条目补充高置信度功能标签。
正文节选
Finding new antimicrobial peptides Rising antimicrobial resistance is one of the most pressing global health crises of our time and could result in an estimated 10 million annual deaths globally by 2050. To prevent this, we urgently need to discover novel therapeutics. Antimicrobial peptides (AMPs), particularly bacteriocins, offer a promising alternative to traditional antibiotics because they have naturally evolved to target fundamental vulnerabilities in competing bacteria, from cell envelope