AlphaFold 未解决蛋白质折叠：DeepMind 与 Biohub 谈 AI 生物学
原标题：Why AlphaFold Didn't Solve Protein Folding — Pushmeet Kohli, Google DeepMind & Sal Candido, Biohub
AI 摘要
Google DeepMind 的 Pushmeet Kohli 与 Biohub 的 Sal Candido 在 Latent Space 的一场对谈中讨论了 AI 驱动生物学的前景与局限。他们指出 AlphaFold 的突破只是起点，蛋白质折叠问题远未解决，仅靠扩大算力和数据不足以理解生物学。两人还探讨了在生物数据中寻找缩放定律、蛋白质语言模型中的隐藏知识、从单个蛋白质建模走向整个生物系统，以及实现治愈所有疾病需要 10 倍级突破而非渐进改进。
正文节选
From the Bitter Lesson of AI scaling to the unsolved mysteries of protein folding, Google DeepMind’s Pushmeet Kohli and Biohub’s Sal Candido are rethinking what it takes to build AI that truly understands biology. In this special panel moderated by Brandon Anderson, they explore why AlphaFold’s breakthrough was only the beginning, why scaling compute and data alone won’t solve biology, and how the next generation of AI models could transform our understanding of proteins, cells, and human diseas