AI工具Co-Scientist助力发现肝纤维化治疗药物
原标题：Uncovering repurposed medicines to fight liver fibrosis
AI 摘要
斯坦福大学遗传学家Gary Peltz使用谷歌的Co-Scientist工具，从现有药物中筛选出可治疗肝纤维化的候选药物。在发表于《Advanced Science》的研究中，Co-Scientist提出的三种候选药物中有两种在实验室测试中有效，其中抗癌药伏立诺他阻断了91%的损伤反应。相比之下，Peltz自己挑选的两种药物均无效。该研究表明AI辅助药物重定位的潜力，可能推动新一代抗纤维化药物的开发。
正文节选
Liver fibrosis is a scarring process that can lead to cirrhosis, which causes more than 1.4 million deaths each year. Geneticist Gary Peltz at Stanford University School of Medicine is using Co-Scientist to accelerate the hunt for medicines that can slow, stop, or reverse it. In research published in Advanced Science, Peltz’s team explored whether Co-Scientist could support efforts to identify drugs from the vast literature of existing medicines that could be repurposed to treat fibrosis. Peltz